Samprix

What AI can a Mac mini (M5 Pro) with 64 GB run?

A Mac mini (M5 Pro) with 64 GB can give a local model 48 GB of memory. At a 4K context, 42 of the 42 models we track fit entirely on it; the largest is Qwen2.5 72B.

Apple Specs last checked: how
Your computer
Context length
Memory a model can use 48 GB 75% of 64 GB unified memory · source

Models on this machine

  • Model file
  • Context
  • Allowance
  • Your GPU memory

Fits

42
Memory needed = model file + context + a 0.5 GB allowance (our estimate). See methodology.

Frequently asked questions

What’s the biggest AI model a Mac mini (M5 Pro) with 64 GB can run?

Qwen2.5 72B (Q4_K_M, a 47 GB download) is the largest of the 42 models we track that fits entirely in the 48 GB a Mac mini (M5 Pro) with 64 GB can give a model at a 4K context, with 2.5 GB to spare and room for up to 12,215 tokens of context.

How much memory can a Mac mini (M5 Pro) with 64 GB give an AI model?

About 48 GB: 75% of its 64 GB of unified memory, because macOS and your other apps share the same memory. The 64 GB is from Mac mini tech specs (checked Oct 2, 2026); the 75% is our estimate.

How fast will local AI run on a Mac mini (M5 Pro) with 64 GB?

Hardware makers and model publishers don’t publish tokens-per-second figures, so there is no source we could cite. We only show whether a model fits and how much context it leaves room for.

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© 2026 Samprix. Not affiliated with OpenAI, Anthropic or Google.

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